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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMNAT1
All Species:
20.3
Human Site:
Y254
Identified Species:
34.36
UniProt:
Q9HAN9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAN9
NP_073624.2
279
31932
Y254
Y
I
E
K
H
N
L
Y
S
S
E
S
E
D
R
Chimpanzee
Pan troglodytes
XP_001168527
254
29013
S231
E
K
H
N
L
Y
S
S
E
S
E
D
R
N
A
Rhesus Macaque
Macaca mulatta
XP_001118727
179
20456
S156
E
K
H
N
L
Y
S
S
E
S
E
D
R
N
A
Dog
Lupus familis
XP_536739
279
31883
Y254
Y
I
E
K
H
D
L
Y
S
C
E
S
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPA7
285
32337
Y255
Y
I
E
K
H
E
L
Y
N
T
E
S
E
G
R
Rat
Rattus norvegicus
Q0HA29
307
34426
T271
P
M
S
V
V
S
S
T
K
S
R
L
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507826
272
31049
K249
V
I
L
A
P
L
Q
K
H
S
Q
E
A
R
Q
Chicken
Gallus gallus
XP_417605
284
32371
Y259
Y
I
E
K
N
D
L
Y
S
L
E
S
E
D
R
Frog
Xenopus laevis
NP_001091188
278
32072
Y253
Y
I
Q
N
H
E
L
Y
S
E
E
S
E
E
K
Zebra Danio
Brachydanio rerio
Q6PC93
304
34191
T268
P
M
S
I
V
S
S
T
K
S
R
L
A
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651315
389
43777
F282
Y
I
K
R
Q
R
L
F
N
F
K
S
K
Y
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91851
223
25149
K200
R
A
A
I
M
N
K
K
S
I
K
Y
S
T
P
Sea Urchin
Strong. purpuratus
XP_783084
287
32645
P263
K
S
V
K
Y
L
I
P
E
P
V
V
K
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53204
395
44891
I371
Y
L
L
P
N
S
V
I
R
Y
I
Q
E
Y
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
62
86.3
N.A.
80.6
28.6
N.A.
63.7
69.7
60.9
26.9
N.A.
33.9
N.A.
26.1
47.3
Protein Similarity:
100
89.6
62.3
92.1
N.A.
89.4
48.5
N.A.
76.3
82
76.3
46.7
N.A.
48
N.A.
44
67.9
P-Site Identity:
100
13.3
13.3
80
N.A.
73.3
6.6
N.A.
13.3
80
60
6.6
N.A.
26.6
N.A.
13.3
6.6
P-Site Similarity:
100
20
20
93.3
N.A.
86.6
26.6
N.A.
26.6
93.3
80
26.6
N.A.
66.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
0
0
0
0
0
22
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
0
0
0
0
15
0
15
0
% D
% Glu:
15
0
29
0
0
15
0
0
22
8
50
8
43
15
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
15
0
29
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
50
0
15
0
0
8
8
0
8
8
0
0
0
8
% I
% Lys:
8
15
8
36
0
0
8
15
15
0
15
0
15
0
8
% K
% Leu:
0
8
15
0
15
15
43
0
0
8
0
15
0
15
0
% L
% Met:
0
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
22
15
15
0
0
15
0
0
0
0
15
8
% N
% Pro:
15
0
0
8
8
0
0
8
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
0
8
0
8
0
0
0
8
8
0
0
22
% Q
% Arg:
8
0
0
8
0
8
0
0
8
0
15
0
15
8
29
% R
% Ser:
0
8
15
0
0
22
29
15
36
43
0
43
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
8
0
0
0
8
0
% T
% Val:
8
0
8
8
15
0
8
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
0
8
15
0
36
0
8
0
8
0
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _